Safety ST-gel

ST-gel is highly safe, providing high adhesiveness and electrical conductivity while having low skin-irritating properties.

Our unique polymerization reaction control technologies have allowed us to form extremely safe polymer networks where unreacted substances in the gel (residual monomers, etc.) are greatly reduced. In addition, the products are composed of ingredients and materials which are verified as being safe, resulting in an extremely safe product.

Test Details	Test Purposes	CR・SR	HIT	AG
Residual Monomer Ratio (ppm)	Indexing of rash and skin problem causes	50 or less	50 or less	50 or less
Acute Oral Toxicity Testing	Toxicity and hazards when accidentally ingested	LD50>2000mg/kg	No data	LD50>10ml/kg (Gel extracts)
Cellular Toxicity	Toxicity to living organisms	0	0	1

(Samples of values measured by Safe Pharm Lab. and Japan Food Research Laboratories)

Skin Irritation for each Grade of Gel

Test Details	Test Purposes	CR, SR Gels	HIT Gels	AG Gels
Primary Skin Irritation Testing	Skin contact irritation	P.I.I. 0.0*	P.I.I. 0.0*	P.I.I. 0.0*
Allergy occurrence rate	Toxicity and hazards when accidentally ingested	No sensitizing properties	No sensitizing properties	No sensitizing properties

*Primary skin irritation testing results showed Non Irritation.

Assessment of Rash Conditions on Human Skin

<24 Hour Open Patch Test>

(Test Methods)

Test material was affixed to the inside of the upper arm of 20 test subjects.
The area where the material is affixed is visually inspected after the material is affixed for 24 hours and replica samples collected only from those that show no abnormalities visible to the naked eye.
The entire visual field of replica specimens is then microscopically examined 50 time magnification.
The results are then split into 4 stages, from A-Stage to D-Stage, based on irritation severity, observed and judged.

Kawai Method "24 Hour Open Patch Test" 3B-0C-OD

Patch Test Microscopic Observation Evaluation Criteria

Evaluation Method	Microscopic Evaluation						Naked Eye Evaluation
Skin Surface Morphological Changes	Round ridges	Depressed skin grooves				Shallow skin grooves Disappearing skin grooves Irregular skin ridges and grooves Wrinkled skin ridges Lamellar ichthyosis	Erythema Edema Papula
Irritation Rank	A-Stage	B-Stage				C-Stage	D-Stage
Evaluation Criteria	-	(Test Subject Irritation Index)-(Control Irritation Index)				1 case or more	1 case or more
		≤ 0	1～2	3	≥ 4	1 case or more	1 case or more
			Mostly negative	Mostly positive	Positive	Positive	Positive

: Normal epidermal replica image

: A-Stage

: B-Stage

: C-Stage